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Are you looking to book up a cruise? Then look at our Mediterranean cruises departing from Rome. Thanks to this amazing trip, you can take in one of the most amazing cities in the world. At the same time, you can easily take in what was once a prime seat of governance for much of Europe. It’s for this reason that Rome is such a fine city to begin any cruise from.

You are not only guaranteed to have a tremendous time at sea; you are going to enjoy a much more satisfying experience overall. The end result? Absolute bliss!

We see many people booking up Mediterranean cruises departing from Rome today. The reason why is simple; they wish to take in much of the Mediterranean, but also experience one of its crown jewels. If you want to make sure that you have a tremendous time at sea whilst taking in the richness of Roman life, then book up for this kind of Mediterranean cruise.

You’ll be able to take in the richness of Rome and all that it offers. It also allows you the time that you need to really put in place the perfect starting point for transport.

Mediterranean Cruises Departing from Rome

One of the most challenging aspects of getting involved with any kind of Mediterranean cruise is setting up where to start. With Rome, you know that you are setting off on your journey from a rich and engrossing city. The kind of cultural capital that makes it easy for you to appreciate both past and present.

From the depth of the ancient architecture to the amazing venues that still stand from the Roman Empire, you’ll find yourself surrounded by a marvellous city. Add in the fact that you can experience everything from a trip to the Coliseum to the modern equivalent in the Stadio Olimpico, home to AS Roma and SS Lazio, two of the most prominent Italian football clubs.

Outside of culture and sport, Rome is a city with a rich nightlife and a tremendous cultural heart. From exploring old museums and seeing sights of what was once the hub of the most powerful empire on the planet, this gives you a way to enjoy a truly iconic capital of European culture.
From one capital, you then head to the next. Our Mediterranean cruises departing from Rome take in all manner of locations across the Mediterranean. This allows you to compare and contrast some of the richest and most stunning cities in the world, making it easy for you to put together a truly remarkable experience.
You can sail to all manner of different locations, too. Simply take a look at the options we have, and book up the Mediterranean cruise for you. Not only that, but this makes it very easy for you to make the right call and to start really moving forward with a dream vacation.
Don’t just settle for either Rome or the Mediterranean; combine both in a special cruise!

Spain, Cannes & Italy
 Wednesday 24th April 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaview
 Twin From $1,775 pp
 Quad From $4,060 pp
Rome to Barcelona
 Wednesday 24th April 2024
Departing Rome (Civitavecchia)  
 11 Nights
 Norwegian Escape
Drinks, WiFi, Dining Included  Drinks, WiFi, Dining Included
 Amazing Included Value
 Twin From $1,702 pp
 Quad From $2,372 pp
Rome (Civitavecchia) to Barcelona
 Friday 26th April 2024
Departing Rome (Civitavecchia)  
 10 Nights
 Norwegian Dawn
 Twin From $2,236 pp
 Quad From $3,251 pp
Italy, Spain & Marseille
 Sunday 28th April 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaside
 Twin From $1,525 pp
 Quad From $3,980 pp
Greece, Malta and Italy
 Monday 29th April 2024
Departing Rome (Civitavecchia)  
 10 Nights
 Norwegian Epic
Drinks, WiFi, Dining Included  Drinks, WiFi, Dining Included
 Amazing Included Value
 Twin From $1,646 pp
 Quad From $2,596 pp
Italy, France & Spain
 Tuesday 30th April 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Fantasia
 Twin From $1,505 pp
 Quad From $1,300 pp
Spain, Cannes & Italy
 Wednesday 1st May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaview
 Twin From $3,735 pp
 Quad From $2,920 pp
Italy, Spain & Marseille
 Sunday 5th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaside
 Twin From $5,185 pp
 Quad From $4,070 pp
Mediterranean
 Monday 6th May 2024
Departing Rome (Civitavecchia)  
 10 Nights
 Norwegian Viva
Drinks, WiFi, Dining Included  Drinks, WiFi, Dining Included
 Amazing Included Value
 Twin From $2,089 pp
 Quad From $3,154 pp
Italy, France & Spain
 Tuesday 7th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Fantasia
 Twin From $1,405 pp
 Quad From $1,560 pp
Spain, Cannes & Italy
 Wednesday 8th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaview
 Twin From $1,585 pp
 Quad From $1,780 pp
Greece, Malta and Italy
 Thursday 9th May 2024
Departing Rome (Civitavecchia)  
 10 Nights
 Norwegian Epic
Drinks, WiFi, Dining Included  Drinks, WiFi, Dining Included
 Amazing Included Value
 Twin From $1,994 pp
 Quad From $2,955 pp
Italy & Spain
 Thursday 9th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 Oasis Of The Seas
 Amazing Included Value
 Twin From $2,457 pp
 Quad From $1,835 pp
Rome to Naples
 Friday 10th May 2024
Departing Rome (Civitavecchia)  
 6 Nights
 MSC Divina
 Twin From $1,237 pp
 Quad From $1,222 pp
Greece, Izmir & Naples
 Friday 10th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Divina
 Twin From $1,705 pp
 Quad From $1,860 pp
Italy, Spain & Marseille
 Sunday 12th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaside
 Twin From $1,705 pp
 Quad From $2,270 pp
Italy, Croatia & Montenegro
 Monday 13th May 2024
Departing Rome (Civitavecchia)  
 11 Nights
 Celebrity Constellation
 Premium Cruise Line
 Twin From $2,216 pp
 Quad From $1,279 pp
Greece & Turkey
 Monday 13th May 2024
Departing Rome (Civitavecchia)  
 14 Nights
 Queen Victoria
Cunard Sale  Cunard Sale
 Premium Cruise Line
 Twin From $3,103 pp
 Quad From $2,676 pp
Rome (Civitavecchia) to Istanbul
 Monday 13th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 Queen Victoria
Cunard Sale  Cunard Sale
 Premium Cruise Line
 Twin From $1,648 pp
 Single From $2,884 pp
Rome (Civitavecchia) to Cagliari
 Monday 13th May 2024
Departing Rome (Civitavecchia)  
 6 Nights
 MSC Musica
 Twin From $697 pp
 Quad From $1,037 pp
Italy, France & Spain
 Tuesday 14th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Fantasia
 Twin From $1,505 pp
 Quad From $2,115 pp
Spain, Cannes & Italy
 Wednesday 15th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaview
 Twin From $1,665 pp
 Quad From $1,820 pp
France, Italy & Spain
 Thursday 16th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 Oasis Of The Seas
 Amazing Included Value
 Twin From $2,062 pp
 Quad From $1,486 pp
Greece, Izmir & Naples
 Friday 17th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Divina
 Twin From $1,835 pp
 Quad From $1,770 pp
Italy, Greece & Kusadasi (Ephesus)
 Friday 17th May 2024
Departing Rome (Civitavecchia)  
 9 Nights
 Odyssey Of The Seas
 Amazing Included Value
 Twin From $3,491 pp
 Quad From $2,463 pp
Greece, Malta and Italy
 Sunday 19th May 2024
Departing Rome (Civitavecchia)  
 10 Nights
 Norwegian Epic
Drinks, WiFi, Dining Included  Drinks, WiFi, Dining Included
 Amazing Included Value
 Twin From $2,110 pp
 Quad From $3,076 pp
Italy, France & Spain
 Monday 20th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Musica
 Twin From $1,315 pp
 Quad From $2,310 pp
Italy, France & Spain
 Tuesday 21st May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Fantasia
 Twin From $1,745 pp
 Quad From $3,810 pp
Spain, Cannes & Italy
 Wednesday 22nd May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaview
 Twin From $1,695 pp
 Quad From $1,940 pp
Greece, Izmir & Naples
 Friday 24th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Divina
 Twin From $1,705 pp
 Quad From $1,870 pp